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This cut-point is recommended for identifying patients with clinically significant change in the physical impact of MS.18 The Symbol Digit Modalities Test (SDMT) was used as a measure of cognition performance outcome.19 An 8-point or greater worsening of the SDMT, which has been suggested for identifying meaningful cognitive decline,20 was defined as cognitive disability worsening

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Research funded by the National Institutes of Health in 2022 revealed that long-term use of e-cigarettes can impair blood vessel function, increasing the risk of cardiovascular disease

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