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This protective effect involves upregulation of antioxidant enzymes and maintenance of mitochondrial membrane potential, indicating Dihexa activates endogenous cellular defense mechanisms that guard against neuronal injury

E.Gonzlez-RuzK.IzquierdoM.Garca-HermosoA.et al (2020)

Essential for maintaining sterility in lyophilized research compounds

By contrast, other GH-axis compounds occupy different regulatory positions: tesamorelin is FDA-approved for a narrow HIV-associated lipodystrophy indication, and sermorelin retains a special status from its prior FDA approval