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N-acetylcysteine (NAC) is a precursor of L-cysteine, an amino acid essential for the synthesis of glutathione
However, the chemical composition of GSH does not allow it to be taken orally for central nervous system diseases because little to none crosses the blood-brain barrier
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Water(Aqua), Glycerin, Butylene Glycol, Niacinamide, Propanediol, Methylpropanediol, Caprylic/Capric Triglyceride, 1,2-Hexanediol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Alcohol Denat., PVP, Polysorbate 20, Ammonium Acryloyldimethyltaurate/VP Copolymer, Glutathione, Sorbitan Isostearate, Ethylhexylglycerin, Fragrance(Parfum), Menthyl Lactate, Adenosine, Glycine, Disodium EDTA, Serine, Glutamic Acid, Melia Azadirachta Leaf Extract, Aspartic Acid, Leucine, Melia Azadirachta Flower Extract, Leucojum Aestivum Bulb Extract, Curcuma Longa (Turmeric) Root Extract, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Valine, Threonine, Proline, Isoleucine, Histidine, Methionine, Cysteine, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Tocopherol, Ascorbic Acid
A double-blind, randomized controlled trial using 2% topical oxidized glutathione (GSSG) demonstrated significant skin-lightening effects after 10 weeks ( Watanabe et al., Clinical, Cosmetic and Investigational Dermatology, 2014 )
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