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Wrapper/binder: homogenized tobacco leaf (reconstituted tobacco, not a whole natural leaf like a premium cigar) Filler: pipe tobacco, which is what produces the sweeter, more aromatic smoke compared to a traditional cigar's whole-leaf filler Tip: plastic or wood, depending on the variety Flavored versions add flavoring to the tobacco itself (see flavors below)

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Nevertheless, assessing effect size through meta-analysis was challenging due to significant heterogeneity among complex interventions across Cochrane reviews and clinical trials

arent even declared as vaping products