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Nicotine and other chemicals in cigarettes restrict blood circulation, which suppresses the immune system and slows down the overall healing process

The big advantage was that most of us came from that same school of low-low-budget filmmaking, so everybody had a lot of experience throwing stuff together on the fly. Burton, too, had had some experience creating low-budget effects whilst making Hansel and Gretel for Disney, as well as his intervening projects especially Frankenweenie (with its $1 million budget) and Aladdin (with its ultra-short shooting time)

Moreover, smoking weakens the immune system, making the body less efficient at fighting allergens

Fortunately, both also can be remedied with routine exams