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Device type may have implications for nicotine exposure, given nicotine salts found in cartridge-based devices make consumption of higher doses of nicotine more palatable 14

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However, a small fraction converts into a toxic metabolite called NAPQI (N-acetyl-p-benzoquinone imine)

Targeted delivery of the probiotic Saccharomyces boulardii to the extracellular matrix enhances gut residence time and recovery in murine colitis