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Once harvested, the briar must be boiled and dried to remove sap and moisture, but the process is long and must be carefully controlled to prevent the briar blocks from drying too quickly, which can result in splits or fissures in the wood

Age, sex, race, and income were considered potential confounders in the relationship between smoking status and the occurrence of disorders based on a theoretical framework illustrated in the constructed Directed Acyclic Graph (DAG) (Supplementary file Figure 1)