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95% less represents the average reduction in levels of a range of harmful chemicals, excluding nicotine, as compared to the smoke of a reference cigarette

Analyzed pipes were selected from archaeological contexts spanning several thousand years ( SI Appendix , Table S1), from the historical period (AD 19001950), and the following Snake River archaeological phases: Numpu (AD 17501900), Piqnin (AD 13001750), Harder (500 BCAD 1300), and Tucannon (2500500 BC)

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Guidelines adopted in 2010 for the implementation of articles 11 and 13 of the Convention recommend that Parties consider introducing plain packaging measures