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Interestingly, the change in squeeze between pre- and post-exposure to the cigarette did not predict latency to smoke according to the authors, it could be that abstaining from smoking for 6 hours was the main factor influencing participants craving rather than the in-lab exposure to a cigarette

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TS extract from these cigarettes also induced an inflammatory response in BBB ECs as demonstrated by increased IL-6 and MMP-2 levels and up-regulation of vascular adhesion molecules, such as VCAM-1 and PECAM-1