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Factors Influencing Nicotine Metabolism Interindividual Variability: The nicotine metabolism rate is a very different phenomenon among people

Researchers who combined data from more than 320,000 adults found that people who smoked 25 cigarettes daily had about a 50% higher risk of heart failure and a roughly 60% greater risk of death from any cause, compared with people who never smoked

"[The] mix of chemicalsnot nicotinecause the serious health effects," says the Food and Drug Administration (FDA)

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