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In 2013, the Food and Drug Administration (FDA) announced a change in NRT labeling to reflect the feasibility and safety of engaging in dual NRT/ cigarette smoking for a period of time

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Furthermore, chronic inflammation due to long-term smoking may promote liver fibrosis and other pathological changes 30,31 , accelerating the progression of viral hepatitis

Thomas AM, Gleber-Netto FO, and Fernandes GR, et al (2014) Alcohol and tobacco consumption affects bacterial richness in oral cavity mucosa biofilms BMC Microbiol 14 250 PMID: 25278091 PMCID: 4186948 59