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Importantly, high-potency cannabis products and purified THC extracts are increasingly consumed during adolescence, a period of profound neurodevelopmental vulnerability [8, 9]

This creates a clinical paradox: heavy drinkers require more alcohol to reach equivalent subjective intoxication while their livers sustain greater cumulative damage per episode

After the administration, distribution of 10 mg/kg of GR in rodents plasma and different tissues was in the range of 530 min (Li et al., 2019a)

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