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Lastly, although female mice are generally more resistant to DIO and glucose intolerance, we observed no sex differences in the percentage of body weight loss in CNS GLP-1R KO mice treated with mGIPR-Ab/P1

We then sought to determine how HIF-1 knockdown influences the effects of Exendin-4 on glycolytic gene expression

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6-10 GLP-1 receptor agonists work to lower glycemia via several mechanisms

Eur J Immunol 19:14431448 Robertson H, Dinkova-Kostova AT, Hayes JD (2020) NRF2 and the ambiguous consequences of its activation during initiation and the subsequent stages of tumourigenesis