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Dysregulation of glycolysis in aging ECs and atherosclerosis Senescent ECs exhibit upregulation of glycolysis [19, 32], which may initially support energy requirements of migration and proliferation [19], but becomes maladaptive under pathological conditions

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For both cell types we observed similar expression of GPX3 on transcript level, comparable to expression of ATP-dependent RNA helicase DHX8 (DHX8) used as endogenous control 45 (Fig

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