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Nebivolol: pharmacologic profile of an ultraselective, vasodilatory beta1-blocker

To ensure optimal FcRn binding, cellular transport, and PK properties of albumin-based biologics, we attempted to substitute the C-terminal L585 of albumin with an amino acid residue that would not be recognized by CPA

Regulation of vasomotor functions and arterial blood pressure GLP-1 has been demonstrated to modulate peripheral arterial blood flow by exerting direct effects or via signals from the CNS