A notable research effort, known as the STEP (Semaglutide GLP-1 Treatment Effect in People with Obesity) trial, revealed that participants taking Semaglutide GLP-1 achieved an average weight reduction of around 15% of their starting body weight within 68 weeks, unlike those taking a placebo
However, they will not address any underlying causes of the headache, like dehydration
TRIUMPH-1 also included a 24-week extension period for about 500 adults with a BMI (body mass index) of 35 or greater, which is classified as severe obesity
My biggest side effect was nausea, which still wasnt that big
Additionally, some patients report vivid dreams or unusual dream content, though this is anecdotal and not documented in clinical trials