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Tribes are already very aware of the health and community impacts of commercial tobacco and have created campaigns, such as Keep It Sacred as a means of refocusing Native American tobacco use back to cultural tradition rather than deadly commercial tobacco use

It found rapid adoption by James Buchanan Dukes American Tobacco Company, which eventually split into R.J

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These results emphasize that other ENDS compounds, independently of nicotine, may additionally contribute to these detrimental cardiovascular effects [41, 83]