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Additionally, C11-BODIPY staining indicated that GCLC overexpression restored lipid peroxidation levels in cells expressing shACTL6A, phenotypes remained significant when treated with erastin and was reversed by Fer-1 (Fig

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Their efficacy is modulated by intraprocedural resistance dynamics (R), sphingolipid metabolism, and inflammasome pathways, establishing a novel local ablation-systemic immunity paradigm for solid tumors