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The inhaled aerosols, commonly referred to as juices, may contain a number of potentially toxic or damaging substances

COMT (catechol-O-methyltransferase) gene variants that reduce prefrontal dopamine availability impair top-down inhibitory regulation of reward-seeking, increasing the probability that early gateway substance use will progress to compulsive drug-seeking behavior in the presence of substance availability

These approaches increasingly shape social norms and influence consumption patterns, particularly among young people and other vulnerable groups

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While electronic cigarettes are considered less harmful than their combustible brethren, studies show they attract new users to nicotine products and may lead to the adoption of traditional cigarettes