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Several investigations have shown that ROS can cause inflammation by activating the transcription factor NF-kB, which activates innate immune responses generating proinflammatory cytokines, such as IL-1, IL-6

However, the limited ability of ex vivo proliferation impedes with its application

BMC Med Genomics 18 , 160 (2025)

The risks of injecting unlicensed, often poorly manufactured compounds are real and not adequately offset by the potential benefits, particularly when well-evidenced alternatives are available

The specific mechanisms by which tDCS influences brain activity are complex and multifactorial and have not yet been fully elucidated