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This is particularly true in the interior northwest Plateau and northern and central northwest coast of North America, places where indigenous tobaccos (which tend to thrive in warmer, drier climates) are scarce (9, 14)

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Phytophthora diversity in the Cape Floristic Region Exserohilum turcicum - Zea mays interaction. Calonectria species

Among former and current HTP users who used them for three years or longer without smoking conventional cigarettes, the risk of metabolic syndrome was 2.17-fold higher than among non-HTP users