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2.3 Mechanisms and consequences of UV radiation-induced modulation of immunity Modulation of the immune system occurs through the direct or indirect activation of cells that reside within the epidermis and dermis, including epidermal keratinocytes, dendritic cells such as Langerhanss cells, dermal lymphocytes, nerves, and mast cells [12]

Davis' performance in the film earned her nominations for the Academy Award for Best Actress, the BAFTA Award for Best Actress in a Leading Role and the Golden Globe Award for Best Actress in a Motion Picture Drama

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