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The colonists were unable to find any profitable commodities and they still depended upon the Indians and sporadic shipments from England for food

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Since the Civil War, dominant firms have widely and repeatedly used exclusive agreements to exert, expand, and fortify their market power

This was seen during the Ebola outbreak of 20132015, when two vaccines were fully developed in advance of clinical trials but only one (the simian adenovirus-based Ebola vaccine ChAd3-EBO-Z) was tested early enough in the outbreak to obtain sufficient clinical data (254)