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doi:10.1007/s10067-006-0433-9 [17] Maes M, Mihaylova I, Kubera M

Additionally, hormonal changes occur that can increase hunger signals and reduce satiety, making it progressively more challenging to maintain a caloric deficit

More realistic than pure cell cultures because the complete tissue architecture is preserved, but less definitive than a human clinical trial

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In a previous system of classification that used homology to mammalian PRX isoforms, subfamily AhpC-PRX was subdivided into isoforms PRX1-4 41,45