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On the other hand, this may be an advantage, as we did not try to establish a single value to be written in stone

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Nicotine may slightly affect blood flow, but these products lack the oxidative stress and toxins from cigarettes that drive most smoking-related shedding

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Here is the formula to calculate the exact equivalence: Nicotine in Traditional Cigarettes: A standard cigarette contains 10mg to 12mg of nicotine