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This study aimed to examine the longitudinal trajectory of these symptoms, classify distinct symptom cluster profiles, uncover symptom interconnections, identify core symptoms, and explore associated factors

Therefore, it is suggested to researchers and clinicians that seeking the means to prevent or treat CIPN may become the key to effectively controlling cancer and improving the quality of life of cancer survivors

Highlighting the strong link between inflammation-related epithelial metabolism and Gcg expression, mRNA levels of Hk2 and Ddit4 , genes involved in glycolysis and suppressing mammalian target of rapamycin (mTOR) activity (67, 68), negatively correlated with Gcg expression, while a positive correlation was observed for Pck1 and Hmgcs2 , genes involved in gluconeogenesis and ketogenesis, respectively ( Figure 4E )

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Pharmaceuticals Suitable pharmaceuticals for encapsulating in liposomes using the cryogenic method of the present invention include, for example, natural and synthetic compounds having the following therapeutic activities: anti-arthritic agents, antiarrhythmic agents, antibacterial agents, Anticholinergic, anticoagulant, antidiuretic, antidote, antiepileptic, antifungal, antiinflammatory, antimetabolite, antimigraine, antitumor, antiparasitic, antipyretic, anti Anticonvulsants, antisera, antispasmodics, analgesics, anesthetics, beta-blockers, biological response modifiers, bone metabolism regulators, cardiovascular drugs, diuretics, enzyme drugs, ovulation inducers, growth promoters, hemostatics , Hormone drugs, Hormone inhibitors, Hypercalcemia improvers, Hypocalcemia improvers, Hypoglycemia improvers, Hyperglycemia improvers, Immunosuppressants, Immunity enhancers, Muscle relaxants, Neurotransmitters, Parasympathetic nerves Agonist, sympathomimetic, plasma expander, plasma augmentation, psychotropic , Thrombolytic agents and vasodilators