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Both are used based on strong preclinical evidence, favorable safety data, and growing clinical experience

Nevertheless, the specific metabolic importance of glutamine in tumorigenesis and tumor growth has also been reported 194,195,196 , and these studies have led many researchers to target glutamine metabolism for the treatment of cancer 8

however, this represents early-phase evidence only, and the mechanistic effects observed in trials including increased energy expenditure and lipolysis via glucagon receptor agonism have not yet been fully characterised in long-term human studies

J Clin Exp Hepatol [Internet]

Data analysis NMR spectra were apodized (0.5 Hz), Fourier transformed, followed by phase and baseline correction in iNMR 3.6 (Mestrelab)