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Constipation with or without other features of voiding dysfunction was often the initial sign of gastrointestinal involvement, but problems such as hemorrhoids, rectal bleeding, and anal fissures were uncommon and more serious complications such as rectal prolapse or fecal impaction did not occur

Clinically isolated syndrome is an inflammatory demyelinating disorder of the central nervous system, and the first clinical episode predicting the possible occurrence of MS

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3391 requires a report from the Secretary of Health and Human Services to detail pediatric research projects and any advances made in pediatric medicine that were funded by Kids First