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It exhibits lower binding to IGFBPs, leading to longer receptor availability and persistent signaling as compared to wild-type IGF-1 that could explain some variations in potency seen under laboratory conditions
Summary Keywords antioxidant, bronchiectasis, COPD, cystic fibrosis, mucolytic, N-acetylcysteine Citation Barne M, Shevade M, Bhattacharyya P, Christopher DJ, Nair S, Abhyankar N, Halder I, Vora A, Khanna A, Swarnakar R, Chhajed P, Santhalingam B, Nair A and Salvi S (2026) N-acetylcysteine: evidence based consensus document on the therapeutic advantages in respiratory diseases (NECTAR)
It has also been studied as part of a combination therapy for stroke, where, when combined with epidermal growth factor, it can reduce brain infarct size and improve neurological outcomes [12]
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