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However, your body needs to get used to absorbing nicotine through your gums, and a high dose of nicotine may be too intense at first and could lead to irritation

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In immortalised human bronchial epithelial cells with normal P53 and KRAS genes, which model normal airways, the high-nicotine medium generated using e-cigarette vapour was toxic, reducing cell growth and triggering cell death, but it did not cause the cells to develop cancerous behaviours, according to Park

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