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Description

With once-daily liraglutide, another GLP-1 receptor agonist approved for the treatment of type 2 diabetes at doses of up to 1.8 mg, body weight and sex were found to be the most important covariates for exposure which, however, did not influence liraglutide PK to any clinically relevant degree [13]

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Additionally, the trial design may lead to higher screening failure rates in non-White populations and thus trial populations may not be representative

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The most frequently reported side effects were nausea or vomiting (37.3%) and constipation (15.6%), and no new safety concerns were identified

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