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Cigarette smoke impairs endothelial function due to vagal input from the airway rather than a specific smoke constituent The ability of blood vessels to widen was examined in the rat study before and after exposure to smoke from four types of classic combustible cigarettes: conventional nicotine, reduced nicotine, conventional nicotine with added menthol, and reduced nicotine with added menthol
For those who criticize Juul's high nicotine content, Kwong noted that pods come in two strengths -- 5% and 3% nicotine concentrations -- letting users customize their "switching journey." Last Monday, the Food and Drug Administration reprimanded Juul for promoting its products as being safer than cigarettes without FDA permission
