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Pathophysiology and therapy of experimental stroke

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It has been suggested, based largely on work in animal models, that enduring changes in GABA A Rs expression induced by developmental exposure to steroid hormones, such as progesterone and its metabolites play a role in hippocampal neuronal excitability and in the etiology of sex-dependent neuropsychiatric disorders and memory deficits later in life (209211)

95% CI = 1.112.58) than among infants with DS and no heart defect, suggesting that lack of maternal folic acid supplementation is associated with septal defects in infants with DS (Bean et al., 4), and no meta-analysis of the data is yet possible

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