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This is where compliance gets messy

The younger people were when they started smoking, the more likely they were to be smoking daily in their 20s and less likely to have quit by their 40s, the research found

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If the FDA were more precise about its standard, it would likely become clear that the evidential requirements are so demanding or burdensome that the comparative efficacy hurdle is, in practice, insurmountable

That setback, however, only proved to be the start of something greater