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In our previously published smaller cEDS cohort [7], a lower incidence of gJHM was observed in adults compared to younger individuals, suggesting that age affects JHM also in cEDS, as more widely demonstrated in hEDS and in which an age-dependent BS was introduced in the revised diagnostic criteria [1, 50, 69, 71,72,73]

Chi-squared tests were used to compare these rates by sex and by race/ethnicity respectively

[4] L&M was the fourth-largest cigarette brand in the world, with 92 billion cigarettes produced in 2007

[DOI] [PMC free article] [PubMed] [Google Scholar] 129.Hasan KM, Friedman TC, Shao X, Parveen M, Sims C, Lee DL, et al