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In xCT-deficient mice, LPS-induced DCs maturation and inflammatory status were significantly reduced compared to wild-type mice, which may be related to changes in the amount of cysteine transferred into the cell or glutamate transferred out of the cell by xCT (145)

The inhibition of the ETC by resveratrol could maintain the ubiquinone pool and complex I more reduced, increasing the chances of electron leaking and the formation of reactive oxygen species (ROS) [7]

The goal is to get a higher concentration of the peptide at the target location

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