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Nicotine replacement therapy, known as NRT, has been used to help people safely quit smoking for more than 20 years

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The review underscores the role of cigarette smoke, particularly polycyclic aromatic hydrocarbons (PAHs), in modulating the metabolic pathways of antidiabetic drugs, primarily through the induction of cytochrome P450 (CYP450) enzymes and uridine diphosphate (UDP)-glucuronosyltransferases (UGTs), thus impacting drug pharmacokinetics and therapeutic outcomes

PMID 19008791

By the end of December 2014, of the 20 slim cigarette brands CTJIs Nanjing was the largest, with sales volume reaching 138,300 cases, or a 49.5% market share, followed by CTHIs Yellow Crane Tower with 78,100 cases, or 27.9%, and CTSIs Mount Tai with 28,400 cases, or 10.2%