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haptocorrin) and passes into the duodenum where the R protein is removed by pancreatic proteases and free cobalamin binds to R protein (IF)

However, no research directly compares continuous use versus cycling protocols (such as 12 weeks on, 4-8 weeks off), leaving optimal long-term strategies somewhat uncertain

There is no limit for the intake of vitamin B12 because the risk of toxicity or overdoes is extremely low

Most patients undergo weekly injections for 4-12 weeks as part of a comprehensive weight management plan

In severe cases, B12 deficiency can lead to neurological symptoms, these can include: tremors, seizures, or ataxia (a loss of coordination)