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The takeaway is this: adopting this eating pattern while using semaglutide doesnt just support weight loss (and it does), it promotes whole-body health in the long term

However, GLP-1RAs are expensive and can potentially widen health disparities as obesity disproportionally affects marginalised racial, ethnic, and socioeconomic communities

Of these patients, 63% ( n = 152) were prescribed a SGLT2 inhibitor ( n = 127) or GLP-1 RA ( n = 25) (Fig

Compared with placebo, tirzepatide 15 mg was the most efficacious treatment in reducing HbA 1c (mean difference 21.61 mmol/mol [1.96%]) followed by tirzepatide 10 mg (20.19 mmol/mol [1.84%]), semaglutide 2.0 mg (17.74 mmol/mol [1.59%]), tirzepatide 5 mg (17.60 mmol/mol [1.60%]), semaglutide 1.0 mg (15.25 mmol/mol [1.39%]) and semaglutide 0.5 mg (12.00 mmol/mol [1.09%])

For reference, the CDC recommends a minimum of 150 minutes of moderate aerobic activity and two strength training sessions each week