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If the medication freezes, the proteins can break down, making the drug ineffective

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Clinicians treating obesity should screen for the presence of eating disorder psychopathology before prescribing GLP-1RAs, as these medications are contraindicated in cases of overweight or obesity associated with atypical anorexia nervosa, bulimia nervosa, and subthreshold bulimia nervosa

Peptide restrictions were introduced during the Biden administration, when FDA officials found the drugs did not meet the safety requirements

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