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Aberrant Partial Chromosomal Instability With Chemotherapeutically Resistant Metachronous Colorectal Cancer Following a Synchronous Primary Colorectal Cancer: A Case Report

de Pablo, P

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Mechanistically, hyperactivation of Drp1 suppresses hexokinase 1 (HK1), a glycolytic enzyme localized to the mitochondria, inducing metabolic reprogramming that promotes NLRP3-driven inflammation and oligodendrocyte pyroptosis (Pradeepkiran and Reddy, 2020

[DOI] [PubMed] [Google Scholar] 22.Yun J, Mullarky E, Lu C, Bosch KN, Kavalier A, Rivera K, Roper J, Chio II, Giannopoulou EG, Rago C, Muley A, Asara JM, Paik J, et al