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for 10 min, 25 L of agonist was dispensed into the well using a FlexStation III microplate reader (Molecular Devices), and the intracellular calcium change was recorded at an excitation wavelength of 485 nm and an emission wavelength of 525 nm

Tirzepatide showed greater reductions in HbA1c and body weight at week 52, along with a lower risk of hypoglycemia [67]

Moreover, the incremental cost-effectiveness ratios (ICERs) were estimated at $2,247 per 1% reduction in HbA1c and $237 per additional kilogram of body weight loss

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Melatonin suppresses ferroptosis via activation of the Nrf2/HO-1 signaling pathway in the mouse model of sepsis-induced acute kidney injury