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Abbreviations AAb+: Autoantibody positive AFM: Afamin ApoB: Apolipoprotein B-100 ApoC1: Apolipoprotein C1 ApoL1: Apolipoprotein L1 BMI-SDS: BMI expressed as standard deviation score CETP: Cholesteryl ester transfer protein F2: Prothrombin FDR: False discovery rate GPx: Glutathione peroxidase GPX3: Glutathione peroxidase 3 GSH: Glutathione HGFAC: Hepatocyte growth factor activator HRG: Histidine-rich glycoprotein IGFBP1: IGF-binding protein 1 IGFBP2: IGF-binding protein 2 IGFBP3: IGF-binding protein 3 INNODIA: Innovative approaches to understanding and arresting type 1 diabetes LMM: Linear mixed effects model MASP2: MBL associated serine protease 2 MMTT: Mixed meal tolerance test ND: Newly diagnosed with type 1 diabetes PPAR: Peroxisome proliferator-activated receptor QC: Quality control Se: Selenium SERPING1: Plasma protease C1 inhibitor SRM: Selected reaction monitoring TGFBI: TGF--induced protein ig-h3 TTR: Transthyretin UFM: Unaffected family member References Rodriguez-Calvo T, Richardson SJ, Pugliese A (2018) Pancreas pathology during the natural history of type 1 diabetes

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There are two main pathways for cysteine catabolism: one is via its enzymatic breakdown to produce H 2 S and organic intermediates that will serve as carbon sources, and the second is via oxidative metabolism through cysteine dioxygenase (CDO)

today BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from a sequence naturally present in the gastric juices of mammals