Both produce dramatic weight loss in clinical trials
Besides inclusion in the essential list, Menghaney also highlighted that, along the lines of the National Viral Hepatitis Control Program (NVHCP), the Union Health Ministry could negotiate prices for these therapies on behalf of state governments, which could then offer the drugs free of cost to patients, depending on their budgets
Furthermore, GLP-1 receptor agonists induce anti-inflammatory effects that could attenuate the low-grade inflammation that underlies obesity, PsO, and HS (reviewed recently in the context of PsO and psoriatic arthritis).68 Finally, improved metabolic control and cardio-renal protection could be beneficial for reducing CVR and managing comorbidities such as DT2 or metabolic syndrome
People who take certain medications may also be at risk of vitamin B12 deficiency, including, but not limited to, estrogen, H2 receptor antagonists, PPIs (Proton Pump Inhibitors), Chloramphenicol, and Metformin
Furthemore, LY294002 abolished GLP-1Rs anti-apoptotic effect (Fig
