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Evidence from animal and human models suggests that gut microbial communities play a role in neuroinflammation and -synuclein aggregation

Translating mitochondria-targeted antioxidant therapies into clinical applications faces a number of challenges

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Structural models were calculated using modified CNS protocols in the ARIA/CNS setup 53,54 , similar as described for the FOXO4 FH -FOXO4 CR3 structure determination pipelne 42