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For this reason, its strongly advised to use a backup birth control method for 4 weeks after starting tirzepatide and after every dose increase

During the dose escalation phasespanning 16 weeks for Wegovy's weight management formulationappetite suppression generally intensifies as the dosage increases

A majority of the digestive side effects of semaglutide tend to be most frequent and intense at the beginning of treatment or during dose escalation

A key concept here is functional hypothalamic amenorrhoea (FHA) , a condition in which the hypothalamus reduces its secretion of gonadotrophin-releasing hormone (GnRH), leading to lower levels of luteinising hormone (LH) and follicle-stimulating hormone (FSH)

Patients should be instructed to clean the injection site with alcohol and allow it to dry before injection