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Acknowledgements This work was supported by the National Natural Science Foundation of China (82504878 and 82474218), National Administration of Traditional Chinese Medicine (zyyzdxk-2023004), and China Postdoctoral Science Foundation (2024M752181)

The benefits appeared to be slightly stronger in healthy individuals (rather than those with medical problems), when single organisms were used (rather than combinations), and when the treatment duration was eight weeks or longer

Statistical differences of P 0.05 were considered to be significant

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mutans by secreting farnesol and polysaccharides [188, 194]