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Natural compounds such as sulforaphane, found in cruciferous vegetables, have gained prominence for their ability to activate the Nrf2-Keap1 pathway, promoting the transcription of genes encoding antioxidant enzymes, such as SOD and CAT, reinforcing the adaptive cellular response to oxidative stress [34, 35]

The word comes from the Latin ligare , to bind. Whether a ligand switches a receptor on, off, or somewhere in between defines its pharmacological class

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Unknown Hormonal Interactions: while not directly androgenic, changes in energy regulation may influence hormone pathways indirectly