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References Acetyllevocarnitine Hydrochloride for the Treatment of Diabetic Peripheral Neuropathy: A Phase 3 Randomized Clinical Trial in China

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Key findings from the Phase 2 trial included: Dose-dependent reductions in body weight across all active treatment arms Significant improvements in waist circumference, a key marker of visceral adiposity Reductions in fasting insulin levels and HbA1c Improvements in lipid profiles, including triglycerides Phase 3 trials are currently ongoing and are expected to include larger, more diverse populations with more granular subgroup analyses, including sex-specific data

Dual agonists that target both GLP-1 and GIP receptors provide a more comprehensive metabolic effect than single-receptor medications