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We recognize that while DiViD donors were in better diabetic control during and prior to biopsy, deceased donors from cadaveric and autopsy pancreas may have experi-enced variable degrees of unavoidable metabolic fluctuations, hyperglycaemia-driven oxidative and nitrosative stress and cold ischaemia before pancreas sampling

It includes physical barriers such as the skin and mucous membranes, as well as specialized organs, tissues, and cells that allow these agents to be detected and neutralized if they bypass the physical barriers

Res.) to match the weight loss of GLP-1MK-801 ( n = 8 mice and n = 4 cages) or vehicle (isotonic saline, n = 8 mice and n = 3-4 cages) for 14 days